Custom antibody-oligonucleotide conjugatesmade for your assay
AbOliGo manufactures custom AOCs to your antibody, your oligo, and your assay requirements — with quantitative QC release, 20 µg minimum starting material, and a days-not-weeks turnaround.
Get a Custom AOC QuoteOff-the-shelf AOCs rarely fit a custom assay
Pre-made antibody-oligo conjugates lock you in to a fixed clone, a fixed oligo barcode, and a degree of labelling chosen for a generic application. When your panel calls for a specific antibody-oligo pair — a new clone, your own barcode, a tuned DoL — the catalogue stops being useful.
Most CROs that quote custom AOC conjugation take six to ten weeks and demand 100 µg+ of starting antibody. That works if you already know exactly what you need and have material to burn. It does not work when you are designing a panel, screening candidates, or working with limited antibody stock.
A custom AOC service built around three things
Fast, small-scale, and QC-released — every conjugate, every order.
Days, not weeks
Our process is designed for custom work from the start, so your conjugate is not queued behind a bulk production run.
From 20 µg
Validate a new antibody-oligo combination without committing 100 µg of precious antibody stock to find out if it works.
Quantitative QC release
Degree of labelling, purity, free oligo and batch-to-batch consistency — measured, not assumed. Every conjugate ships against the same criteria.
How a custom AOC project runs
Consultation
Tell us your antibody, oligo sequence, and target application. We define scope, QC release criteria, and timeline.
Conjugation & QC
We perform the antibody-oligonucleotide conjugation, purify your AOC at µg-to-mg scale, then validate against quantitative release criteria.
Dispatch
Your QC-released conjugate ships ready for immediate use, with a release report covering every criterion measured.
What we conjugate
The chemistry is workflow-agnostic. Tell us what you are building and we will tune the conjugate to it.
Antibodies
- Monoclonal and recombinant antibodies
- Any host species
- Different isotypes
- Your antibody, or sourced on your behalf
Oligonucleotides
- Custom barcode sequences
- Application-specific oligo designs
- Tuned oligo:antibody ratios (DoL)
- Compatible with PLA, CODEX, cyclic IF, CITE-seq, multiplex IHC and more
Who orders custom AOCs from us
- Researchers building custom multiplexed panels for spatial biology, CODEX, cyclic IF, multiplex IHC or PLA
- Teams that need a specific antibody clone paired with their own oligo barcode design
- Single-cell and proteomics groups who have outgrown off-the-shelf AOC catalogues
- Core facilities supplying multiple PIs on predictable timelines
- Diagnostics and assay-development teams scoping a reagent before scaling
Scope your custom AOC
Tell us about your antibody, oligo, and target assay. We will reply with scope, timeline and pricing.
Request a custom AOC quote
Share a few details about your antibody, oligo and target assay — we will reply with scope, timeline and pricing.