Custom Conjugation Service

Every Conjugate QC-Released.Every Batch.

AbOliGo applies quantitative release criteria to every custom antibody-oligonucleotide conjugate — so you get consistent, assay-ready reagents, not guesswork.

Get a Custom Conjugation Quote

A conjugate that works once and fails the next time wastes more than reagent

It wastes the staining run, the tissue section, and the time spent troubleshooting whether the problem is the conjugate or the assay. When there are no clear release criteria, every new batch is an unknown.

Multiplexed panels are only as reliable as the weakest conjugate. A single inconsistent AOC can compromise an entire staining run.

What QC-released actually means

Quantitative release criteria are not a line on a spec sheet. They determine whether a conjugate ships.

Degree of labeling confirmed

We measure and tune the oligo:antibody ratio to your target application, not to a generic default.

Purity validated

Conjugates are purified and checked so unconjugated antibody and free oligo do not carry over into your assay.

Batch-to-batch consistency

The same QC criteria are applied every time, giving you a conjugate you can compare across experiments.

Precise control over degree of labeling

Figure 1: dual DNA and protein gel staining showing tunable degree of labelling for AbOliGo antibody–oligonucleotide conjugates. — Figure 1. AbOliGo's antibody–oligo conjugation workflow enables controlled tuning of the degree of labelling (DoL). Manipulating the conjugation conditions produces an increased gel shift of the antibody–oligo conjugate, consistent with higher oligo loading for both 15-mer (lanes 3 to 5) and 32-mer oligos (lanes 6 to 8). Dual gel staining (DNA and protein) confirms both antibody and oligo content within the conjugate, while the absence of unbound oligo demonstrates effective post-conjugation purification. Ab = antibody alone.

How it works

Define your requirements

We work with you to set the target product profile: antibody, oligo, application, DoL range, and release criteria.

Conjugation & validation

Your AOC is manufactured at µg-to-mg scale and validated against the agreed QC spec before anything ships.

Consistent re-orders

Need more? The same process and release criteria apply, so batch 5 matches batch 1.

Works with your antibodies

Monoclonal and polyclonal antibodies across a wide range of host species and isotypes
Custom DoL tuning optimised for your workflow, not adapted from someone else’s
Starting from just 20 µg of antibody — enough to validate before committing to larger volumes
Turnaround in days so validation cycles stay on schedule

100%

QC-released

Every batch

Same criteria applied

20 µg

Minimum starting material

Days

Not weeks

Stop troubleshooting your conjugates

Tell us what you are working on and we will scope a QC-released conjugation that meets your requirements.

Request a QC-Released Conjugation Quote

Share your antibody and target application — we will respond with scope and quantitative release criteria.