Antibodies

Anti-14-3-3 alpha/beta Antibody-Oligo Conjugate

SKU: aoc1035

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Assay

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5'
3'
0/256

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Antibody Target

Target
14-3-3 protein beta/alpha
UniProt Number
P31946
Target Description
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13..
Molecular Weight
28kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC1453
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseRat