Antibodies
Anti-Calmodulin 1/2/3 Antibody-Oligo Conjugate
SKU: aoc1381
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Assay
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5'
3'
0/256
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Antibody Target
- Target
- Calmodulin-1
- UniProt Number
- P0DP23
- Additional Target Information
- This antibody also binds Calmodulin-2, Uniprot:P0DP24. This antibody also binds Calmodulin-3, Uniprot:P0DP25.
- Target Description
- Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Is a regulator of voltage-dependent L-type calcium channels. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. Forms a potassium channel complex with KCNQ1 and regulates electrophysiological activity of the channel via calcium-binding. Acts as a sensor to modulate the endoplasmic reticulum contacts with other organelles mediated by VMP1:ATP2A2.; FUNCTION: (Microbial infection) Required for Legionella pneumophila SidJ glutamylase activity.; FUNCTION: (Microbial infection) Required for C.violaceum CopC and S.flexneri OspC3 arginine ADP-riboxanase activity.
- Molecular Weight
- 16 kDa
Antibody Characteristics
- Clonality
- Monoclonal
- Application
- WBIF-PELISA
- Clone
- ARC0316
- Isotype
- IgG
- Form
- Liquid
- Immunogen
- Synthetic peptide. This information is considered to be commercially sensitive.
- Immunogen Species
- Human
- Host Species
- Rabbit
- Species Reactivity
- HumanMouseRat