Antibodies

Anti-Cip4 Antibody-Oligo Conjugate

SKU: aoc1676

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Assay

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5'
3'
0/256

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Antibody Target

Target
Cdc42-interacting protein 4
UniProt Number
Q15642
Target Description
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL..
Molecular Weight
68kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC2844
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouse