Antibodies

Anti-Connexin 43 Antibody-Oligo Conjugate

SKU: aoc1721

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Assay

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5'
3'
0/256

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Antibody Target

Target
Gap junction alpha-1 protein
UniProt Number
P17302
Target Description
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity)..
Molecular Weight
43 kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC58819
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseRat