Antibodies

Anti-Cyclin H Antibody-Oligo Conjugate (ARC2823)

SKU: aoc1788

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Assay

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5'
3'
0/256

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Antibody Target

Target
Cyclin-H
UniProt Number
P51946
Target Description
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle..
Molecular Weight
38kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC2823
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouse