Antibodies

Anti-DKK3 Antibody-Oligo Conjugate (ARC52093)

SKU: aoc1889

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Assay

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5'
3'
0/256

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Antibody Target

Target
Dickkopf-related protein 3
UniProt Number
Q9UBP4
Target Description
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity)..
Molecular Weight
38kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBIF-PELISA
Clone
ARC52093
Isotype
IgG
Form
Liquid
Immunogen
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseRat