Antibodies

Anti-ENTPD5 Antibody-Oligo Conjugate (ARC2210)

SKU: aoc1982

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Assay

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5'
3'
0/256

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Antibody Target

Target
Nucleoside diphosphate phosphatase ENTPD5
UniProt Number
O75356
Target Description
Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP (PubMed:10400613, PubMed:15698960). In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER (By similarity)..
Molecular Weight
48kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC2210
Isotype
IgG
Form
Liquid
Immunogen
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
MouseRat