Antibodies

Anti-mGluR2 Antibody-Oligo Conjugate

SKU: aoc2708

Select the oligo sequence you'd like conjugated to this antibody, and we'll deliver the antibody-oligo conjugate in record time. The antibody-oligo conjugate will be released using ensuring batch to batch consistency.

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  • Consistent conjugation performance
  • Flexible antibody and oligo pairing
  • Fast conjugation turn around time
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Assay

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5'
3'
0/256

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Antibody Target

Target
Metabotropic glutamate receptor 2
UniProt Number
Q14416
Target Description
Dimeric G protein-coupled receptor which is activated by the excitatory neurotransmitter L-glutamate. Plays critical roles in modulating synaptic transmission and neuronal excitability. Upon activation by glutamate, inhibits presynaptic calcium channels, reducing further glutamate release and dampening excitatory signaling. Mechanistically, ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.; FUNCTION: (Microbial infection) Plays an important role in influenza virus internalization.; FUNCTION: (Microbial infection) Acts as a host entry factor for rabies virus that hijacks the endocytosis of GRM2 to enter cells.; FUNCTION: (Microbial infection) Acts as a host entry factor for SARS-CoV-2 that hijacks the endocytosis of GRM2 to enter cells.
Molecular Weight
96 kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBIF-PELISA
Clone
ARC2070
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
MouseRat
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