Antibodies

Anti-Nesprin3 Antibody-Oligo Conjugate

SKU: aoc2855

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Assay

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5'
3'
0/256

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Antibody Target

Target
Nesprin-3
UniProt Number
Q6ZMZ3
Target Description
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Molecular Weight
112kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC3013
Isotype
IgG
Form
Liquid
Immunogen
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouse