Antibodies

Anti-NUP98 Antibody-Oligo Conjugate

SKU: aoc2940

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Assay

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5'
3'
0/256

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Antibody Target

Target
Nuclear pore complex protein Nup98-Nup96
UniProt Number
P52948
Target Description
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body).; FUNCTION: (Microbial infection) Interacts with HIV-1 capsid protein P24 and nucleocapsid protein P7 and may thereby promote the integration of the virus in the host nucleus (in vitro). Binding affinity to HIV-1 CA-NC complexes bearing the capsid change Asn-74-Asp is reduced (in vitro).
Molecular Weight
198kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC58955
Isotype
IgG
Form
Liquid
Immunogen
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseMonkey