Antibodies

Anti-p47phox/NCF1 Antibody-Oligo Conjugate

SKU: aoc2979

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Assay

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5'
3'
0/256

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Antibody Target

Target
Neutrophil cytosol factor 1
UniProt Number
P14598
Target Description
Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox.
Molecular Weight
45kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC1206
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
Human