Antibodies
Anti-Phospho-YWHAZ -Ser58+YWHAH -Ser59+YWHAG-Ser59+YWHAB -Ser60 Antibody-Oligo Conjugate
SKU: aoc3971
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Assay
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5'
3'
0/256
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Antibody Target
- Target
- 14-3-3 protein zeta/delta
- UniProt Number
- P63104
- Additional Target Information
- This antibody also binds 14-3-3 protein eta, Uniprot:Q04917. This antibody also binds 14-3-3 protein gamma, Uniprot:P61981. This antibody also binds 14-3-3 protein beta/alpha, Uniprot:P31946.
- Target Description
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation. In neurons, regulates spine maturation through the modulation of ARHGEF7 activity.
- Molecular Weight
- 28kDa
Antibody Characteristics
- Clonality
- Monoclonal
- Application
- WBELISA
- Clone
- ARC73529
- Isotype
- IgG
- Form
- Liquid
- Immunogen
- Synthetic peptide. This information is considered to be commercially sensitive.
- Immunogen Species
- Human
- Host Species
- Rabbit
- Species Reactivity
- HumanMouse