Antibodies

Anti-Plexin A1 Antibody-Oligo Conjugate

SKU: aoc3142

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Assay

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5'
3'
0/256

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Antibody Target

Target
Plexin-A1
UniProt Number
Q9UIW2
Target Description
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Acts as coreceptor of TREM2 for SEMA6D in dendritic cells and is involved in the generation of immune responses and skeletal homeostasis.
Molecular Weight
211kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBELISA
Clone
ARC2077
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseRat