Antibodies

Anti-beta 2 Microglobulin Antibody-Oligo Conjugate (ARC0656)

SKU: aoc1330

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Assay

Immunofluorescence Oligossee protocol

IF1 Oligo Details

5'
AATATGGAATTCGTCCGAGCCCGTCAAG
3'

View Paper

Accessory oligo is complementary to only the ab-conjugated oligo

Anti-beta 2 Microglobulin Antibody (ARC0656)-IF1

Antibody Target

Target
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
UniProt Number
P61769
Target Description
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553)..
Molecular Weight
14kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBIF-PIHCELISA
Clone
ARC0656
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseRat