Antibodies

Anti-CD86 Antibody-Oligo Conjugate

SKU: aoc1601

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Assay

Immunofluorescence Oligossee protocol

IF1 Oligo Details

5'
AATATGGAATTCGTCCGAGCCCGTCAAG
3'

View Paper

Accessory oligo is complementary to only the ab-conjugated oligo

Anti-CD86 Antibody-IF1

Antibody Target

Target
T-lymphocyte activation antigen CD86
UniProt Number
P42081
Target Description
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4 (PubMed:12196291). May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation (PubMed:7527824). Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (By similarity)..; FUNCTION: [Isoform 2]: Interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation..; FUNCTION: (Microbial infection) Acts as a receptor for adenovirus subgroup B..
Molecular Weight
38kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBICCFlow CytometryELISA
Clone
ARC54011
Isotype
IgG
Form
Liquid
Immunogen
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
Human