Antibodies

Anti-FBP1 Antibody-Oligo Conjugate (ARC0664)

SKU: aoc2046

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Assay

Immunofluorescence Oligossee protocol

IF1 Oligo Details

5'
AATATGGAATTCGTCCGAGCCCGTCAAG
3'

View Paper

Accessory oligo is complementary to only the ab-conjugated oligo

Anti-FBP1 Antibody (ARC0664)-IF1

Antibody Target

Target
Fructose-1,6-bisphosphatase 1
UniProt Number
P09467
Target Description
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain..
Molecular Weight
37 kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBICCIF-PELISA
Clone
ARC0664
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseRat