Antibodies

Anti-GATA3 Antibody-Oligo Conjugate (ARC0115)

SKU: aoc2140

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Assay

Proximity Ligation Assay Oligossee protocol

PLA1 Oligo Details

5'
[AmC6dT] ACAACAACAAGAATGGAACCTCGCTAGAACGT
3'

View Paper

An AOC with the PLA2 oligo is needed to complete the pairing in a Proximity Ligation Assay.

Anti-GATA3 Antibody (ARC0115)-PLA1

Antibody Target

Target
Trans-acting T-cell-specific transcription factor GATA-3
UniProt Number
P23771
Target Description
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages..
Molecular Weight
48kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBIPELISAChIPChIP-seq
Clone
ARC0115
Isotype
IgG
Form
Liquid
Immunogen
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouse