AntibodiesNeuroMab

Anti-Kv1.1 K+ Channel Antibody-Oligo Conjugate

SKU: aoc20

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Assay

Immunofluorescence Oligossee protocol

IF1 Oligo Details

5'
AATATGGAATTCGTCCGAGCCCGTCAAG
3'

View Paper

Accessory oligo is complementary to only the ab-conjugated oligo

Anti-Kv1.1 K+ Channel Antibody-IF1

Antibody Target

Target
Kv1.1 K+ channel
UniProt Number
Q09470
Target Description
Potassium Channel Kv1.1 or Kcna1 is a member of the Shaker potassium channel family. Kv1.1 is expressed in the brain, CNS and in the kidney. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.1 is involved with the regulation of cellular functions and the control of neuronal excitability. Mutations in Kv1.1 are associated with Episodic ataxia type 1 and epilepsy.
Molecular Weight
85 kDa (major: mature glycosylation)65 kDa (minor: immature glycosylation)
Synonyms
Potassium voltage-gated channel subfamily A member 1 (RBKI) (RCK1) (Voltage-gated potassium channel subunit Kv1.1)

Antibody Characteristics

Clonality
Monoclonal
Application
WBIHCICCIP
Specificity
No cross-reactivity reported
Clone
K20/78
Isotype
IgG1
Form
Liquid
Immunogen
Synthetic peptide amino acids 458-476 (cytoplasmic C-terminus) of rat Kv1.1 (EEDMNNSIAHYRQANIRTG; accession number P10499)
Immunogen Species
Rat
Host Species
Mouse
Species Reactivity
FinchHumanMouseRabbitRat