Antibodies

Anti-SDHA Antibody-Oligo Conjugate

SKU: aoc3391

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Assay

Immunofluorescence Oligossee protocol

IF1 Oligo Details

5'
AATATGGAATTCGTCCGAGCCCGTCAAG
3'

View Paper

Accessory oligo is complementary to only the ab-conjugated oligo

Anti-SDHA Antibody-IF1

Antibody Target

Target
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
UniProt Number
P31040
Target Description
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. Can act as a tumor suppressor.
Molecular Weight
73 kDa

Antibody Characteristics

Clonality
Monoclonal
Application
WBICCIF-PELISA
Clone
ARC0726
Isotype
IgG
Form
Liquid
Immunogen
Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Species
Human
Host Species
Rabbit
Species Reactivity
HumanMouseRat