Characterization

2 articles

Analytical methods for characterizing antibody-oligonucleotide conjugates including SDS-PAGE for DoL assessment and capillary zone electrophoresis.

SDS-PAGE Characterization DoL

Analytical Characterization

A Guide to Using SDS-PAGE to Characterize Antibody-Oligonucleotide Conjugates

Learn how SDS-PAGE can be used to characterize antibody-oligonucleotide conjugates, assess degree of labeling, and troubleshoot conjugation reactions for optimal performance.

12 Nov 2025Read article

CZE Characterization Analytics

Analytical Characterization

Application of Capillary Zone Electrophoresis for the Characterization of Antibody-Oligo Conjugates

Analytical tests that can be utilized for the characterization of antibody-oligonucleotide complexes (AOCs) include gel exclusion chromatography, SDS-PAGE, mass spectrometry, and capillary electrophoresis (CE).

29 Apr 2025Read article

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SDS-PAGE1 DoL2 CZE1 Analytics1